The SCD EXPRESS™ Compression System is a clinically proven modality for the prevention of Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE). The system consists of the SCD EXPRESS™ controller, non-disposable tubing and single patient use leg garments. The compression sleeve contains three bladders to deliver circumferential, sequential and gradient compression to ensure clearance of the deep veins without the risk of distal blood trapping. The sleeve is anatomically designed with adjustable sleeve closure offering a customized fit for each patient. The SCD EXPRESS™ Compression System offers a clinician the option of two different prophylactic methods with one controller; leg compression and foot compression. This new system provides a number of unique features that improve prophylaxis for every patient. The SCD EXPRESS™ Compression System allows one or two limb operation giving the end user more flexibility for prophylaxis options. The battery operation makes the device transportable for uninterrupted protection throughout a patient's stay in the hospital. The more active or ambulating patients can continue the protection without being tethered to a wall outlet.